顺氯氨铂内耳毒性的实验观察

被引:2
作者
顾欣祖
李琦
王丽雯
机构
[1] 第一军医大学第一附属医院耳鼻咽喉科
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
<正> 顺氯氨铂有较强的抑制细菌作用和一定的抗肿瘤作用,可引起消化道反应、骨髓抑制、肾脏损害及内耳中毒,其中以肾脏损害及内耳中毒最为严重。其耳毒性的发生率国外报道为9~91%。以往多数学者认为顺氯
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页码:21 / 23 +79+82
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  • [1] Cis-dichlorodiammineplatinum (Ⅱ) the trail from inert electrode to a theropeutic solution. Magyia FM,et al. Cancer Treatment Reports . 1979
  • [2] Cis-platinum ototoxicity. Hetson L,et al. Clinical Toxicology . 1978
  • [3] Ototoxicity of the anticancer drug cisplatin. Nakai Y,et al. Acta Oto laryngologica . 1982
  • [4] Phase Ⅱ trial of cisplatin in refractory childhood cancer: children’s cancer study group report. Baum ES,et al. Cancer Treatment Reports . 1981
  • [5] Rapid onset hearing loss after cisplatinum therapy. Chapman P,et al. Journal of Laryngology and Otology . 1982
  • [6] Auditory toxicity effects of longterm cisplatin therapy in genitourinary cancer patients. Nila V,et al. Journal of Surgical Oncology . 1981
  • [7] Lanzotti VJ High-dose cisplatin for lung cancer. Bhuchar VK. Cancer Treatment Reports . 1982
  • [8] Cisplatinum ototoxicity (Fren). Peytral CL,et al. Ann Otolaryngol . 1981
  • [9] Cis-platinum vestibular toxicity. Schaefer SD,et al. Cancer . 1981
  • [10] Inhibition of cell division in escherichia coli by electrolysis products from a platinum electrode. Rosenberg B,et al. Nature . 1965