肠内营养混悬液对重症脑血管病合并2型糖尿病患者血清蛋白和血脂的影响

被引:15
作者
王薇
冯立群
毕齐
机构
[1] 首都医科大学附属北京安贞医院神经内科
关键词
重症脑血管病; 糖尿病; 肠内营养支持;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)]; R587.1 [糖尿病];
学科分类号
100201 [内科学]; 100204 [神经病学];
摘要
目的探讨不同组分的肠内营养液对重症脑血管病合并糖尿病患者和未合并糖尿病患者营养指标的影响。方法需要进行持续肠内营养的重症脑血管病患者57例,根据是否合并糖尿病分为两组,分别予以糖尿病专用剂型肠内营养液和非糖尿病剂型肠内营养液14 d,对两组患者的血清蛋白及血脂等相关指标进行前瞻性研究。结果两组患者在入院基线资料基本一致的情况下,在入院7 d、14 d时,两组患者的血清总蛋白(P=0.017,P=0.006)、清蛋白(P=0.044,P=0.010)、前清蛋白(P=0.016,P=0.013)、总胆固醇(P=0.009,P=0.007)、高密度脂蛋白(P=0.016,P=0.025)和低密度脂蛋白(P=0.018,P=0.011)比较,差异均有统计学意义,而血红蛋白在入院14d时差异才有统计学意义(P=0.018);两组的三酰甘油水平(7 d,P=0.625;14 d,P=0.169)差异无统计学意义。结论重症脑血管病患者进行持续肠内营养时,糖尿病患者应用糖尿病专用剂型虽然能较好地控制血糖,但低蛋白血症出现早,血清蛋白、血红蛋白及血胆固醇均较非糖尿病组出现快速下降。有必要改进糖尿病专用剂型的蛋白及脂肪组成比例,以保证糖尿病患者处于应激状况下的能量需求。
引用
收藏
页码:1896 / 1899
页数:4
相关论文
共 8 条
[1]
Effect of the dietary fat quality on insulin sensitivity [J].
Galgani, Jose E. ;
Uauy, Ricardo D. ;
Aguirre, Carolina A. ;
Diaz, Erik O. .
BRITISH JOURNAL OF NUTRITION, 2008, 100 (03) :471-479
[2]
Immunomodulation by n-3-versus n-6-rich lipid emulsions in murine acute lung injury - Role of platelet-activating factor receptor [J].
Schaefer, Martina Barbara ;
Ott, Juliane ;
Mohr, Andrea ;
Bi, Ming Hua ;
Grosz, Andrea ;
Weissmann, Norbert ;
Ishii, Satoshi ;
Grimminger, Friedrich ;
Seeger, Werner ;
Mayer, Konstantin .
CRITICAL CARE MEDICINE, 2007, 35 (02) :544-554
[3]
Diabetes specific tube feed results in improved glycaemic and triglyceridaemic control during 6<ce:hsp sp="0.16"/>h continuous feeding in diabetes patients.[J].Zandrie Hofman;Mirian Lansink;Carlette Rouws;Jenneke D.E. van Drunen;Harm Kuipers.e-SPEN; the European e-Journal of Clinical Nutrition and Metabolism.2007, 2
[4]
Impact of hyperglycemia on ischemic stroke mortality in diabetic and non-diabetic patients [J].
Kes, Vanja Basic ;
Solter, Vesna Vargek ;
Supanc, Visnja ;
Demarin, Vida .
ANNALS OF SAUDI MEDICINE, 2007, 27 (05) :352-355
[5]
Low-carbohydrate and high-fat intake among adult patients with poorly controlled type 2 diabetes mellitus.[J].Yunsheng Ma;Barbara C. Olendzki;Andrea R. Hafner;David E. Chiriboga;Annie L. Culver;Victoria A. Andersen;Philip A. Merriam;Sherry L. Pagoto.Nutrition.2006, 11
[6]
Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury [J].
Singer, P ;
Theilla, M ;
Fisher, H ;
Gibstein, L ;
Grozovski, E ;
Cohen, J .
CRITICAL CARE MEDICINE, 2006, 34 (04) :1033-1038
[7]
Omega-3 fatty acids improve the diagnosis-related clinical outcome [J].
Heller, AR ;
Rössler, S ;
Litz, RJ ;
Stehr, SN ;
Heller, SC ;
Koch, R ;
Koch, T .
CRITICAL CARE MEDICINE, 2006, 34 (04) :972-979
[8]
Enteral nutrition with eicosapentaenoic acid, γ-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome [J].
Pacht, ER ;
DeMichele, SJ ;
Nelson, JL ;
Hart, J ;
Wennberg, AK ;
Gadek, JE .
CRITICAL CARE MEDICINE, 2003, 31 (02) :491-500