音乐疗法对卒中后认知障碍的临床疗效

被引:70
作者
王鑫
孙彩花
施伟
杨阳
高长云
机构
[1] 扬州大学医学院附属江苏省扬州五台山医院神经康复科
关键词
音乐疗法; 脑卒中; 认知障碍; 脑源性神经营养因子;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
100204 [神经病学];
摘要
目的探讨音乐疗法对缺血性卒中后认知障碍的临床疗效和相关作用机制。方法选取80例韦氏记忆量表测量值在40~55分之间的缺血性卒中后认知障碍患者分为常规肢体康复治疗组和音乐治疗组,2组分别进行8周常规肢体康复治疗和常规肢体康复治疗合并音乐治疗,并在治疗前后分别予以MoCA量表、Stroop色词测验,以及血清BDNF的测量。结果经过8周康复训练后,常规肢体康复治疗组患者总体认知功能得到显著改善,MoCA量表成绩有显著性提高(P<0.05);反映执行功能的Stroop色词测验成绩的改善情况不明显(P>0.05);血清BDNF蛋白含量有显著性增高(P<0.05);常规肢体康复治疗合并音乐治疗组患者MoCA量表和Stroop色词测验成绩以及血清BDNF的含量均较治疗前显著改善(P<0.01),与同期常规肢体康复治疗组比较,这些指标也有显著性改善(P<0.05)。结论音乐疗法可以改善卒中后认知障碍患者的总体认知功能和执行功能,与神经缺损功能的改善有一定相关性,并能够促进该类患者血清BDNF表达的上调。
引用
收藏
页码:10 / 13+16 +16
页数:5
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