草果提取物对金黄色葡萄球菌抑菌机制的初探

被引：15

作者：

彭美芳

陈文学

李宇真

童惠珠

仇厚援

机构：

[1] 海南大学食品学院

来源：

食品工业科技 | 2013年 / 34卷 / 24期

基金：

海南省自然科学基金;

关键词：

草果提取物; 金黄色葡萄球菌; 抑菌机理;

D O I：

10.13386/j.issn1002-0306.2013.24.014

中图分类号：

R285 [中药药理学];

学科分类号：

1008 ;

摘要：

对草果抑菌物质进行初步提取和分离,研究石油醚萃取物、氯仿萃取物、乙酸乙酯萃取物和正丁醇萃取物对金黄色葡萄球菌生长曲线及膜通透性的影响,探讨草果提取物的抑菌机理。结果表明,乙酸乙酯萃取物和氯仿萃取物最小抑菌浓度最小均为1.25mg/mL,石油醚萃取物为2.5mg/mL,正丁醇萃取物为5mg/mL。在草果提取物最小抑菌浓度作用下,金黄色葡萄球菌生长曲线各时间点的OD值增长不明显,细胞膜通透性有所提高,其中蛋白质含量呈小幅度降低,菌液电导率呈上升趋势。草果提取物能有效地抑制金黄色葡萄球菌的生长,可能与其对金黄色葡萄球菌细胞膜和细胞壁的破坏直接相关。

引用

页码：79 / 82

页数：4

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