药物性肝损伤的临床诊断思路和评估

被引：9

作者：

茅益民

机构：

[1] 上海交通大学医学院附属仁济医院上海市消化疾病研究所

来源：

中华肝脏病杂志 | 2012年 / 03期

关键词：

诊断; 药物性肝损伤; 方法;

D O I：

暂无

中图分类号：

R575 [肝及胆疾病];

学科分类号：

100201 [内科学];

摘要：

<正>药物引起的肝脏损伤具有致残、延长住院时间、甚至危及生命的风险,作为药物安全性问题的一部分,药物的肝脏毒性正受到医学界、社会公众和药监部门的广泛关注和重视。在美国的肝移植中心,药物性肝损伤(drug-induced liver injury,DILI)已超

引用

共 4 条

[1]

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles [J].

Lucena, M. Isabel ;

Molokhia, Mariam ;

Shen, Yufeng ;

Urban, Thomas J. ;

Aithal, Guruprasad P. ;

Andrade, Raul J. ;

Day, Christopher P. ;

Ruiz-Cabello, Francisco ;

Donaldson, Peter T. ;

Stephens, Camilla ;

Pirmohamed, Munir ;

Romero-Gomez, Manuel ;

Maria Navarro, Jose ;

Fontana, Robert J. ;

Miller, Michael ;

Groome, Max ;

Bondon-Guitton, Emmanuelle ;

Conforti, Anita ;

Stricker, Bruno H. C. ;

Carvajal, Alfonso ;

Ibanez, Luisa ;

Yue, Qun-Ying ;

Eichelbaum, Michel ;

Floratos, Aris ;

Pe'er, Itsik ;

Daly, Mark J. ;

Goldstein, David B. ;

Dillon, John F. ;

Nelson, Matthew R. ;

Watkins, Paul B. ;

Daly, Ann K. .

GASTROENTEROLOGY, 2011, 141 (01) :338-347

[2]

Pharmacogenetics of Drug-Induced Liver Injury [J].

Russmann, Stefan ;

Jetter, Alexander ;

Kullak-Ublick, Gerd A. .

HEPATOLOGY, 2010, 52 (02) :748-761

[3]

Drug-related hepatotoxicity and acute liver failure [J].

Murray, Karen F. ;

Hadzic, Nedim ;

Wirth, Stefan ;

Bassett, Mikelle ;

Kelly, Deirdre .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2008, 47 (04) :395-405

[4]

Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-induced Liver Injury in the United States [J].

Chalasani, Naga ;

Fontana, Robert J. ;

Bonkovsky, Herbert L. ;

Watkins, Paul B. ;

Davern, Timothy ;

Serrano, Jose ;

Yang, Hongqiu ;

Rochon, James .

GASTROENTEROLOGY, 2008, 135 (06) :1924-1934

← 1 →