甲状旁腺素促成骨作用的研究进展

被引：4

作者：

李宁

王满宜

贺良

机构：

[1] 北京积水潭医院创伤骨科

来源：

中国骨质疏松杂志 | 2009年 / 15卷 / 10期

关键词：

甲状旁腺素; 骨质疏松; 骨折愈合; 骨形成;

D O I：

暂无

中图分类号：

R580 [];

学科分类号：

摘要：

甲状旁腺素(Parathyroid hormone,PTH)能够调节骨骼的合成代谢和分解代谢过程,通过影响包括成骨细胞、破骨细胞、骨骼内衬细胞、骨细胞等众多种类的细胞系,并激活多种信号途径,从而达到促进骨形成的作用。这取决于低剂量及间断性的给药方式。大量动物试验和临床研究,显示甲状旁腺素可有效的治疗骨质疏松。近年来动物实验发现甲状旁腺素也可有效的促进骨折愈合。甲状旁腺素作为骨形成促进剂,将广泛应用于临床治疗。

引用

页码：778 / 783+772 +772

页数：7

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