睾酮对心肌梗塞大鼠死亡率和左心室功能的影响

被引：1

作者：

雷立权 ^{[1
]}

卢兴 ^{[1
]}

杨继声 ^{[1
]}

邵奇明 ^{[1
]}

邹丽荣 ^{[1
]}

机构：

[1] 西安医科大学病理生理教研室

来源：

中华医学杂志 | 1987年 / 06期

关键词：

心肌梗塞; 睾酮;

D O I：

暂无

中图分类号：

R542 [];

学科分类号：

1002 ; 100201 ;

摘要：

观察了肌注宰酮对心肌梗塞(MI)雄鼠死亡率及左宝功能的影响。经睾酮处理的梗塞(MI+T)组左冠状动脉结扎后24小时内的死亡率较对照梗塞(MI)组减少 48%(P<0.05)。两组梗塞范围虽无明显差异,但术后第1、3、9天,MI+T组的dp/dt max及-dp/dt max均较MI组明显改善,且术后第9天MI+T组室间隔横截面积及心肌纤维直径也明显大于MI组。结果提示MI后给予睾酮有助于左室功能的代偿和恢复。

引用

共 13 条

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