人参总皂苷的发酵及其产物的抗癌活性研究

被引：9

作者：

崔磊

金护定

尹成日

机构：

[1] 延边大学长白山生物资源与功能分子教育部重点实验室

来源：

延边大学学报(自然科学版) | 2014年 / 40卷 / 04期

关键词：

β-葡萄糖苷酶; 人参茎叶总皂苷; 菌株YS2; 抗癌活性;

D O I：

10.16379/j.cnki.issn.1004-4353.2014.04.009

中图分类号：

S567.51 [];

学科分类号：

摘要：

从土壤中分离得到14种β-葡萄糖苷酶高产菌株,其中菌株YS2能够有效地将人参茎叶总皂苷和人参提取物中的人参皂苷转化为稀有人参皂苷Rg3;菌株YS2和YS7的人参发酵物对结肠癌colon26-M3.1细胞具有较强的抑制作用,其IC50值分别为180μg/mL和170μg/mL.根据ITS序列构建的系统发育树,确定菌株YS2为链格孢属(Alternaria).

引用

页码：314 / 319

页数：6

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