粉末包衣技术在药物制剂领域的应用研究进展

被引：13

作者：

徐晨 ^{[1
]}

谢俊 ^{[2
]}

黄春玉 ^{[2
]}

程娟 ^{[2
]}

周建平 ^{[1
]}

机构：

[1] 中国药科大学药剂学教研室

[2] 南京金陵药业股份有限公司技术中心

来源：

药学进展 | 2013年 / 37卷 / 12期

关键词：

粉末包衣技术; 药物制剂; 表面改性; 缓控释; 稳定性;

D O I：

暂无

中图分类号：

R944 [剂型];

学科分类号：

100702 [药剂学];

摘要：

粉末包衣技术是薄膜包衣技术发展至今的一个重要分支,其在药物制剂领域的应用优势突出,近年来受到药剂学研究者的广泛关注。分类综述目前应用于药物制剂的几种主要粉末包衣技术,包括属于物理化学法中的凝聚法、溶剂蒸发法和熔融分散法以及物理机械法中的喷雾干燥法、喷雾冷凝法、干法包衣技术和气流悬浮包衣技术,并探讨粉末包衣技术的主要功用,如用于制备缓控释制剂、药物粉末表面改性、改善口服制剂感官效果和提高药物及制剂稳定性等。

引用

页码：635 / 641

页数：7

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