宫颈上皮内瘤变Ⅲ级锥切术后病变残留相关因素分析附视频

被引:22
作者
李寒松
魏凤华
申桂华
吕秋波
张毅
机构
[1] 北京医院妇产科
关键词
宫颈上皮内瘤样病变; 原位癌; 宫颈早期浸润癌; 冷刀锥形切除术; 病变残留;
D O I
暂无
中图分类号
R737.33 [子宫肿瘤];
学科分类号
100112 [医学生物化学与分子生物学];
摘要
目的探讨宫颈锥切术后病变残留的高危因素。方法回顾性分析2002年1月至2009年1月经阴道镜宫颈活检诊断为宫颈上皮内瘤样病变(CIN)Ⅲ级(包括重度不典型增生及原位癌)的患者391例,其中197例直接行全子宫切除术,194例行宫颈冷刀锥切,61例CINⅢ在锥切后半年内行全子宫切除,分析61例患者的年龄、产次、锥切标本切缘、腺体受累、多象限受累等与切除子宫标本中残留病变的关系。结果患者平均年龄为38.6岁(26~63岁),平均产次3.1次。单因素分析结果表明,年龄≥50岁、内切缘阳性、多象限受累是与病变残留有显著关系的因素;绝经状态、产次≥3次、宫颈腺体受累与病变残留无显著关系。多因素logistic回归分析结果表明只有内切缘阳性与多象限受累是病变残留的高危因素。结论内切缘阳性与多象限受累是预测锥切术后病变残留的高危因素。在治疗CINⅢ及其治疗后随访过程中,重视并合理利用高危因素。
引用
收藏
页码:39 / 42
页数:4
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