阿司匹林抵抗研究进展

被引:5
作者
王霜
杨正国
机构
[1] 医院一病区
关键词
阿司匹林抵抗;
D O I
10.14172/j.cnki.issn1671-4008.2006.01.072
中图分类号
R971 [神经系统药物];
学科分类号
1007 ;
摘要
<正>阿司匹林1897年问世,最初主要用于疼痛或炎症的治疗,自20世纪70年代发现其对血小板的抑制作用之后,开始作为抗血小板药物广泛用于心脑血管疾病的二级预防及某些选择性患者的一级预防。抗血小板聚集实验者协会回顾分析了超过10万例接受阿司匹林治疗者和未接受治疗者的资料,证实了阿司匹林能使高危血管性疾病患者的病死率、心肌梗死和脑卒中的发生率降低25%,血管移植、动脉阻塞发生率减少48%,肺栓塞发生率减少67%,深静脉血栓发生率减少23%。然而不幸的是,并非所有的患者均能获得一致
引用
收藏
页码:104 / 106
页数:3
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