各类抗骨质疏松药物的临床研究进展

被引：43

作者：

王谦 ^{[1
]}

刘光军 ^{[1
]}

许硕贵 ^{[2
]}

机构：

[1] 医院创伤骨科七区

[2] 上海长海医院骨科

来源：

实用医药杂志 | 2010年 / 27卷 / 04期

关键词：

骨质疏松; 药物治疗; 作用机制; 研究进展;

D O I：

10.14172/j.cnki.issn1671-4008.2010.04.031

中图分类号：

R580 [];

学科分类号：

摘要：

<正>骨质疏松症(osteoporosis,OP)是一种多病因的全身性骨骼疾病,好发于老年人及绝经后妇女,它是指以骨量降低、骨组织微细结构退变导致骨强度下降、骨脆性增加及骨折危险性增大为特征的代谢性疾病。其临床症状多为骨骼疼痛和骨

引用

页码：368 / 371

页数：4

共 12 条

[1]

Treatment of Postmenopausal Osteoporosis.[J].Gayatri Gupta;Wilbert S. Aronow.Comprehensive Therapy.2007, 3

[2]

Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study [J].

Reginster, JY ;

Seeman, E ;

De Vernejoul, MC ;

Adami, S ;

Compston, J ;

Phenekos, C ;

Devogelaer, JP ;

Curiel, MD ;

Sawicki, A ;

Goemaere, S ;

Sorensen, OH ;

Felsenberg, D ;

Meunier, PJ .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2005, 90 (05) :2816-2822

[3]

Hydroxymethylglutaryl-coenzyme A reductase inhibitors and osteoporosis: a meta-analysis [J].

Hatzigeorgiou, C ;

Jackson, JL .

OSTEOPOROSIS INTERNATIONAL, 2005, 16 (08) :990-998

[4]

Soy protein consumption and bone mass in early postmenopausal Chinese women [J].

Ho, SC ;

Woo, J ;

Lam, S ;

Chen, Y ;

Sham, A ;

Lau, J .

OSTEOPOROSIS INTERNATIONAL, 2003, 14 (10) :835-842

[5]

Effect of raloxifene combined with monofluorophosphate as compared with monofluorophosphate alone in postmenopausal women with low bone mass:: a randomized, controlled trial [J].

Reginster, JY ;

Felsenberg, D ;

Pavo, I ;

Stepan, J ;

Payer, J ;

Resch, H ;

Glüer, CC ;

Mühlenbacher, D ;

Quail, D ;

Schmitt, H ;

Nickelsen, T .

OSTEOPOROSIS INTERNATIONAL, 2003, 14 (09) :741-749

[6]

Therapeutic potential of oestrogen receptor ligands in development for osteoporosis.[J].Cho;Nuttall.Emerging Drugs.2001, 1

[7]

Multinational, placebo-controlled, randomized trial of the effects of alendronate on bone density and fracture risk in postmenopausal women with low bone mass:: Results of the FOSIT study [J].

Pols, HAP ;

Felsenberg, D ;

Hanley, DA ;

Stepán, J ;

Muñoz-Torres, M ;

Wilkin, TJ ;

Qin-sheng, G ;

Galich, AM ;

Vandormael, K ;

Yates, AJ ;

Stych, B .

OSTEOPOROSIS INTERNATIONAL, 1999, 9 (05) :461-468

[8]

Comparison of the effects of intermittent and continuous administration of human parathyroid hormone(1–34) on rat bone.[J].T. Uzawa;M. Hori;S. Ejiri;H. Ozawa.Bone.1995, 4

[9]

PREVENTION OF POSTMENOPAUSAL BONE LOSS BY RECTAL CALCITONIN [J].

REGINSTER, JY ;

JUPSIN, I ;

DEROISY, R ;

BIQUET, I ;

FRANCHIMONT, N ;

FRANCHIMONT, P .

CALCIFIED TISSUE INTERNATIONAL, 1995, 56 (06) :539-542

[10]

骨质疏松症的药物防治研究现状 [J].

马慧萍 ;

贾正平 ;

葛欣 ;

陈克明 .

中国药师, 2004, (10) :816-818

← 1 2 →