贝叶斯法与可疑药物不良反应因果评价

被引:9
作者
魏水易
蒯丽萍
顾文华
机构
[1] 第二军医大学药学院
[2] 第二军医大学药学院 上海
[3] 上海
关键词
药物不良反应; 因果关系; 贝叶斯法; 因果评价;
D O I
暂无
中图分类号
R973 [血液和造血系统药物];
学科分类号
1007 ;
摘要
可疑药物不良反应的因果评价是复杂的鉴别诊断过程。导致临床不良事件的原因有药物的,也有非药物的。为了正确识别造成特定不良事件的真正原因,需要用科学、可靠的方法排除许多不确定因素的干扰。贝叶斯法以贝叶斯定理为基础,根据特定药物不良反应病例的资料,估算药物原因的先验概率和后验比,推测具有最大可能性的原因。本文系统介绍了贝叶斯法的原理、基本概念和在药物不良反应因果评价中的实施步骤。
引用
收藏
页码:102 / 106
页数:5
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