小檗碱调节血糖血脂代谢紊乱机制研究进展

被引:45
作者
沈宁
李彩娜
环奕
申竹芳
机构
[1] 中国医学科学院、北京协和医学院药物研究所
关键词
小檗碱; 糖尿病; 胰岛β细胞;
D O I
暂无
中图分类号
R285 [中药药理学];
学科分类号
100806 [中药药理学];
摘要
小檗碱是从中药黄连等中提取的异喹啉类生物碱,长期以来用于治疗腹泻及消化道感染。近年来,陆续有报道小檗碱可对糖尿病代谢紊乱状态发挥有益作用。其机制研究亦涉及疾病发生的多个环节,包括调节血胆固醇、甘油三酯;降低血糖;改善胰岛素抵抗状态;影响胰岛β细胞功能等。
引用
收藏
页码:699 / 704
页数:6
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