阿尔茨海默病的分子发病机制及其治疗研究进展

被引：36

作者：

官志忠 ^{[1
]}

齐晓岚 ^{[2
]}

机构：

[1] 贵阳医学院分子生物学重点实验室

[2] 贵阳医学院病理学教研室

来源：

中华病理学杂志 | 2008年 / 01期

关键词：

D O I：

暂无

中图分类号：

R686 [筋腱、韧带、滑囊疾病及损伤];

学科分类号：

1002 ; 100210 ;

摘要：

<正> 阿尔茨海默病(Alzheimer's disease,AD)是痴呆症中最常见的类型,自从德国神经病理学家 Alois Alzheimer 于1906年首次报道该病以来,对 AD 的认识和研究已经进行了100余年。由β淀粉样肽(β-amyloid peptide,Aβ)沉积形成的老年斑和高度磷酸化 Tau 蛋白聚集构成的神经原纤维缠结是AD 脑组织中典型的神经病理学形态改变,而 Aβ和 Tau 蛋

引用

共 12 条

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