核因子-κB与缺血缺氧所致疾病的关系

被引:4
作者
杜逸亭
董文斌
机构
[1] 四川泸州医学院附属医院新生儿科,四川泸州医学院附属医院新生儿科四川泸州,四川泸州
关键词
核因子-κB; 缺血缺氧;
D O I
暂无
中图分类号
R722.1 [新生儿疾病];
学科分类号
100202 ;
摘要
核因子 κB是细胞中一个重要转录调控因子 ,存在于多种类型的细胞中。机体组织器官受到缺血缺氧的创伤后 ,核因子 κB被激活 ,从胞浆中进入细胞核内 ,结合到被诱导基因启动子序列上的κB位点 ,诱导基因转录 ,参与缺血缺氧导致心脏 ,肾脏 ,脑等重要器官的损伤 ,乃至危及生命。
引用
收藏
页码:209 / 211
页数:3
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