肝移植后病毒性肝炎的复发及肝炎病毒再感染

被引:3
作者
高志良 [1 ]
黄湛镰 [1 ]
杨扬 [2 ]
机构
[1] 中山大学附属第三医院感染性疾病科
[2] 中山大学附属第三医院肝移植科
关键词
肝移植; 肝炎,病毒性; 复发; 再感染;
D O I
暂无
中图分类号
R657 []; R51 [传染病];
学科分类号
100201 [内科学];
摘要
<正>肝移植是目前治疗终末期肝病的有效方法,在我国,病毒性肝炎相关性肝病是接受肝移植患者的主要病因。随着经验的积累,肝移植就手术过程而言已有相当高的成功率,影响术后生存率的主要因素有术后感染、慢性排斥及胆道梗阻、移植后肝炎复发等。众多的研究结果表明,乙型肝炎免疫球蛋白(hepatitis B immunoglogbulin,HBIG)联合核苷(酸)类似物能显著降低肝移植术后HBV再感染率及肝炎复发率,但该方案仍存在HBIG费用昂贵、使用不便及部分抗HBV药物耐药率高等问题。对于丙型肝炎,目前仍没有特效的预
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