Wnt/β-catenin通路在动脉粥样硬化发生发展中的作用

被引：12

作者：

马守原 ^{[1
]}

姚树桐 ^{[2
]}

朱平 ^{[1
]}

秦树存 ^{[2
]}

机构：

[1] 中国人民解放军总医院南楼心血管内科

[2] 泰山医学院动脉粥样硬化研究所山东省高校动脉粥样硬化重点实验室

来源：

中国病理生理杂志 | 2016年 / 32卷 / 03期

关键词：

Wnt/β-catenin信号通路; 动脉粥样硬化;

D O I：

暂无

中图分类号：

R543.5 [动脉疾病];

学科分类号：

100201 [内科学];

摘要：

<正>动脉粥样硬化（atherosclerosis,AS）作为心血管疾病（cardiovascular disease,CVD）的主要病理基础,严重危害人们的健康[1]。AS是多因素、多发病环节参与的慢性炎症性疾病,内皮损伤和功能减退是其发生的启动环节[2],炎症细胞浸润和炎症介质释放、氧化应激反应、血管平滑肌细胞增殖以及泡沫细胞形成和死亡是AS发生发展的关键机制[3]。Wnt通

引用

页码：564 / 568

页数：5

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