Based on the Problems Produced from modern civilization and its rapid development, this paper points out that there exists the inclination of the limits of modern civilization. In the process, the phenomenon of alienation should be studied deeply. In the history, reason is the catalyst of modern civilization. The paper believes that the alienation of reason is just the superficial phenomenon. “Logos” has not the independent power, for the reason is only the tool with the characteristic of sign. Now we must recognize the correct relationship between reason and sense in the human nature configuration to guide sensibility with the reason.