微生物苯丙氨酸解氨酶(PAL)/肉桂酸途径生物转化制L-苯丙氨酸酶源菌种选育

被引：6

作者：

杨敏

杨顺楷

不详

机构：

[1] 不详

[2] 中国科学院成都生物研究所!成都

[3] 不详

[4] 不详

来源：

应用与环境生物学报 | 1999年 / 06期

关键词：

菌种选育; 苯丙氨酸解氨酶(PAL); 肉桂酸生物转化;

D O I：

暂无

中图分类号：

Q946 [植物生物化学];

学科分类号：

摘要：

Phenylalanine ammonia lyase (PAL) has great values in industrial and potential medical applications, especially in the production of L phenylalanine from trans cinnamic acid. Strain breeding is important for the development and applications of this bioprocess. In this article, mutiple ways for breeding of microbial strains containing PAL were reviewed in details, including direction screening, enrichment culture technique for isolating strains from nature sources, phsical and chemical mutagenesis for strain improvement, PAL molecular clone and genetic engineering, etc. The significance of protoplast techniques for breeding of Rhodotorula strains containing PAL was analysed and discussed.

引用

页码：643 / 650

页数：8

共 12 条

[1]

遗传学应用[M]. 高等教育出版社 , 罗鹏主编, 1996

[2]

化学与生命科学[M]. 化学工业出版社 , 惠永正,陈耀全主编, 1992

[3]

普通微生物遗传学[M]. 南开大学出版社 , 丁友栦,陈宁编, 1990

[4]

Screening for microorganism with cell wall lytic activity to produce protoplast-forming enzymes[J] . Wolfgang Kaul,Uwe Rossow,Carl-Christian Emeis.Applied Microbiology and Biotechnology . 1993 (4)

[5]

Synthesis of L-phenylalanine analogs byRhodotorula glutinis. Bioconversion of cinnamic acids derivatives[J] . G. Renard,J -C. Guilleux,C. Bore,V. Malta-Valette,D. A. Lerner.Biotechnology Letters . 1992 (8)

[6]

Phenylalanine ammonia lyase from Sporidiobolus pararoseus and Rhodosporidium toruloides : Application for phenylalanine and tyrosine deamination[J] . World Journal of Microbiology ＆ Biotechnology . 1992 (4)

[7]

Expression in E. coli of the gene encoding phenylalanine ammonia-lyase from Rhodosporidium toruloides[J] . Applied Microbiology and Biotechnology . 1992 (6)

[8] NOVEL STABILIZATION OF PHENYLALANINE AMMONIA-LYASE CATALYST DURING BIOCONVERSION OF TRANS-CINNAMIC ACID TO L-PHENYLALANINE [J].

EVANS, CT ;

CONRAD, D ;

HANNA, K ;

PETERSON, W ;

CHOMA, C ;

MISAWA, M .

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1987, 25 (05) :399-405

[9]

Production of phenylalanine ammonia-lyase （PAL）: isolation and evaluation of yeast strains suitable for commercial production of l -phenylalanine[J] . Christopher T. Evans,Kim Hanna,Dayle Conrad,Wendy Peterson,Masanaru Misawa.Applied Microbiology and Biotechnology . 1987 (5)

[10]

Microbial formation of cinnamic acid from phenylalanine, Agr. Ogata K, Uchiyama K, Yamada H. Biological Chemistry . 1966

← 1 2 →