双膦酸盐类药物引起的下颌骨坏死

被引:13
作者
房桂珍
李为民
刘东刚
机构
[1] 河北医科大学生物医学工程中心
关键词
下颌骨坏死; 双膦酸盐; 药物不良反应;
D O I
暂无
中图分类号
R782 [口腔颌面部外科学];
学科分类号
100302 [口腔临床医学];
摘要
随着双膦酸盐药物(bisphosphonates,BPs)日趋广泛的应用,与BPs相关的下颌骨坏死(osteonecrosis of the jaw,ONJ)也逐渐成为广大临床医师和患者关注的焦点。ONJ的发生与BPs药物种类及治疗时间密切相关,其发生率较高,且不能治愈。因此,早期诊断和预防ONJ的发生显得尤为重要。本文综述ONJ的发生机理与BPs的关系、临床表现和防治原则。
引用
收藏
页码:1069 / 1071
页数:3
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