丝氨酸蛋白酶抑制物vaspin与动脉粥样硬化

被引：3

作者：

张宝伟 ^{[1
,2
]}

彭文辉 ^{[1
]}

徐亚伟 ^{[1
]}

机构：

[1] 上海市同济大学附属第十人民医院心内科

[2] 江苏省镇江市第一人民医院心内科

来源：

中华心血管病杂志 | 2012年 / 11期

关键词：

D O I：

暂无

中图分类号：

R543.5 [动脉疾病];

学科分类号：

1002 ; 100201 ;

摘要：

<正>肥胖与动脉粥样硬化关系密切,而脂肪组织分泌的细胞因子是二者之间的重要"桥梁"。脂肪组织分泌的多种细胞因子,如瘦素、肿瘤坏死因子、抵抗素及内脂素等参与体内的炎症反应,后者与心血管疾病的发生发展密切相关。vaspin是最近发现的一种新的脂肪细胞特异性表达的细胞因子,属于丝氨酸蛋白酶抑制物(senne protease inhibitor,serpin)家族成员之一。研究发现vaspin不仅与肥胖、胰岛素敏感性及2型糖尿病密切相关,而且越来越多的证据发现

引用

页码：973 / 975

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