纳米羟基磷灰石复合物治疗骨缺损的研究进展

被引：14

作者：

孙浩远

宋科官

机构：

[1] 哈尔滨医科大学附属第一医院运动医学科

来源：

中国骨科临床与基础研究杂志 | 2019年 / 11卷 / 05期

基金：

国家重点研发计划;

关键词：

羟基磷灰石类; 纳米复合物; 生物相容性材料; 骨缺损; 壳聚糖; 胶原; 明胶; 丝素蛋白; 高分子聚合物;

D O I：

暂无

中图分类号：

R318.08 [生物材料学]; R687 [矫形外科手术学];

学科分类号：

100103 [病原生物学]; 100220 [骨科学];

摘要：

纳米羟基磷灰石(n HA)具有良好的生物相容性、生物活性和骨传导性,是一种性能优异的骨修复材料,但脆性大、强度低,不适合直接用于骨缺损治疗。近年来随着材料学、组织工程学以及纳米技术的快速发展,nHA复合生物材料逐渐成为骨组织领域的研究热点。本文综述nHA复合骨缺损替代材料的制备、生物相容性、机械性能及其在骨缺损治疗中的应用,旨在为寻找理想的人工骨缺损修复材料提供参考。

引用

页码：300 / 307

页数：8

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