高血糖对大鼠局灶性脑缺血细胞外钙离子的影响

被引:5
作者
刘建荣
胡大萌
赵瑜
余慧贞
黄明智
机构
[1] 上海第二医科大学附属瑞金医院神经内科!
[2] 上海市高血压研究所临床生理研究室!
关键词
高血糖; 局灶性脑缺血; 细胞外钙离子;
D O I
暂无
中图分类号
R363 [病理生理学];
学科分类号
100104 ;
摘要
应用钙离子选择性微电极测定血糖对大鼠局灶性脑缺血后细胞外钙离子浓度的影响。结果发现正常血糖组(n=8)和高血糖组(n=8)在缺血早期已发生细胞外钙离子浓度下降(P<0.01),而缺血15~30min时高血糖组较正常血糖组下降更为显著(P<0.05)。提示高血糖加重脑缺血损伤可能与加强细胞外钙离子内流有关。
引用
收藏
页码:201 / 203
页数:3
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