缺血性脑卒中的病因分型与危险因素

被引：27

作者：

茅翼亭

方堃

董强

韩翔

机构：

[1] 复旦大学附属华山医院神经内科

来源：

中华脑血管病杂志(电子版) | 2009年 / 3卷 / 02期

关键词：

缺血性脑卒中; 危险因素; 卒中亚型;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

1002 ;

摘要：

目的探讨缺血性脑卒中病因分型与不同危险因素的关系。方法回顾性分析连续登记的急性缺血性卒中患者,记录其危险因素,并按急性卒中治疗试验(TOAST)标准将缺血性卒中分为5种类型分析相关危险因素对其发生风险的影响。结果在纳入分析的205例患者中,大动脉粥样硬化性卒中(LAA)100例(48.9%)、心源性卒中(CE)17例(8.3%)、小动脉闭塞性卒中(SAO)38例(18.5%)、其他原因所致卒中(SOE)12例(5.8%)、不明原因卒中(SUE)38例(18.5%)。分析显示,高血压与LAA的发生有关(OR=2.40,P=0.0028);心房颤动对CE发生有显著作用(OR=365.90,P<0.0001);饮酒与SAO的发生可能有一定关联(OR=2.73,P=0.036),而白细胞则在CE患者显著升高(OR=8.00,P=0.0013)。结论不同类型缺血性脑卒中与不同的危险因素有关。该结果对临床个体化预防与治疗有一定提示意义。

引用

页码：68 / 75

页数：8

共 28 条

[1]

Homocysteine and Its Relationship to Stroke Subtypes in a UK Black Population: The South London Ethnicity and Stroke Study[J] . Usman Khan,Carollyn Crossley,Lalit Kalra,Anthony Rudd,Charles D.A. Wolfe,Paul Collinson,Hugh S. Markus.Stroke . 2008 (11)

[2] Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack [J].

Adams, Robert J. ;

Albers, Greg ;

Alberts, Mark J. ;

Benavente, Oscar ;

Furie, Karen ;

Goldstein, Larry B. ;

Gorelick, Philip ;

Halperin, Jonathan ;

Harbaugh, Robert ;

Johnston, S. Claiborne ;

Katzan, Irene ;

Kelly-Hayes, Margaret ;

Kenton, Edgar J. ;

Marks, Michael ;

Sacco, Ralph L. ;

Schwamm, Lee H. .

STROKE, 2008, 39 (05) :1647-1652

[3]

Heart Disease and Stroke Statistics—2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee[J] . Wayne Rosamond,Katherine Flegal,Karen Furie,Alan Go,Kurt Greenlund,Nancy Haase,Susan M. Hailpern,Michael Ho,Virginia Howard,Brett Kissela,Steven Kittner,Donald Lloyd-Jones,Mary McDermott,James Meigs,Claudia Moy,Graham Nichol,Christopher O’Donnell,Veronique Roger,Paul Sorlie,Julia Steinberger,Thomas Thom,Matt Wilson,Yuling Hong.Circulation . 20

[4]

Homocysteine-lowering therapy: a role in stroke prevention?[J] . J David Spence.Lancet Neurology . 2007 (9)

[5]

Acute phase proteins and oxidised low-density lipoprotein in association with ischemic stroke subtype, severity and outcome[J] . Riina Vibo,Janika K＆otilde,rv,Mai Roose,Riina Vibo,Janika K＆otilde,rv,Mai Roose,Priit Kampus,Piibe Muda,Kersti Zilmer,Mihkel Zilmer.Free Radical Research . 2007 (3)

[6]

Risk Factors for Ischemic Stroke Subtypes: The Atherosclerosis Risk in Communities Study[J] . Tetsuya Ohira,Eyal Shahar,Lloyd E. Chambless,Wayne D. Rosamond,Thomas H. Mosley,Aaron R. Folsom.Stroke . 2006 (10)

[7]

Characteristics and six-month outcomes in a cohort of 8288 diabetic and non-diabetic patients with previous history of acute coronary syndrome or stroke: the French PREVENIR 3 survey[J] . B Bouhanick,JP Cambou,J Ferrières,E Amelineau,L Guize.Diabetes and Metabolism . 2006 (5)

[8]

Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association Council on Stroke: Co-Sponsored by the Council on Cardiovascular Radiology and Intervention: The American Academy of Neurology affirms the value of this guideline[J] . Ralph L. Sacco,Robert Adams,Greg Albers,Mark J. Alberts,Oscar Benavente,Karen Furie,Larry B. Goldstein,Philip Gorelick,Jonathan

[9]

Different risk factor profiles between subtypes of ischemic stroke. A case-control study in Korean men[J] . Yun-Mi Song,Sun Uck Kwon,Joohon Sung,Shah Ebrahim,George Davey Smith,Sung Sunwoo,Yeong Sook Yun.European Journal of Epidemiology . 2005 (7)

[10]

Are Lacunar Strokes Really Different?: A Systematic Review of Differences in Risk Factor Profiles Between Lacunar and Nonlacunar Infarcts[J] . Caroline Jackson,Cathie Sudlow.Stroke . 2005 (4)

← 1 2 3 →