基于高通量测序技术分析肠道菌群及其影响因素的研究进展

被引:121
作者
郑艺
张家超
郭壮
张和平
机构
[1] 内蒙古农业大学乳品生物技术与工程教育部重点实验室
关键词
高通量测序; 肠道菌群; 影响因素;
D O I
暂无
中图分类号
R378 [病原细菌];
学科分类号
100103 [病原生物学];
摘要
目前大量研究结果表明肠道菌群组成和功能与宿主健康状态密切相关。应用高通量技术能够更详细、更深层地解析肠道菌群的组成与功能。本文概述了基于高通量测序技术对宿主肠道菌群研究的结果,总结出影响肠道菌群多样性的主要因素,为宿主肠道菌群的研究提供参考。
引用
收藏
页码:157 / 164
页数:8
相关论文
共 8 条
[1]
益生菌对肠道菌群的影响——以Lactobacillus casei Zhang研究为例 [J].
张家超 ;
郭壮 ;
孙志宏 ;
陈卫 ;
张和平 .
中国食品学报, 2011, (09) :58-68
[2]
Diversity and metabolic impact of intestinal Lactobacillus species in healthy adults and the elderly[J] Jelena Štšepetova;Epp Sepp;Helgi Kolk;Krista Lõivukene;Epp Songisepp;Marika Mikelsaar British Journal of Nutrition 2011,
[3]
Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans[J] Ubeda; Carles;Taur; Ying;Jenq; Robert R;Equinda; Michele J;Son; Tammy;Samstein; Miriam;Viale; Agnes;Socci; Nicholas D;van den Brink; Marcel R M;Kamboj; Mini;Pamer; Eric G Journal of Clinical Investigation 2010,
[4]
Evidence-based review of probiotics for antibiotic-associated diarrhea and Clostridium difficile infections[J] Lynne V. McFarland Anaerobe 2009,
[5]
High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity[J] Marie A. Hildebrandt;Christian Hoffmann;Scott A. Sherrill–Mix;Sue A. Keilbaugh;Micah Hamady;Ying–Yu Chen;Rob Knight;Rexford S. Ahima;Frederic Bushman;Gary D. Wu Gastroenterology 2009,
[6]
Intestinal microbiota development in the premature neonate: establishment of a lasting commensal relationship?[J] MakaMshvildadze;JosefNeu;VolkerMai Nutrition Reviews 2008,
[7]
Multiplex quantification of 16S rDNA of predominant bacteria group within human fecal samples by polymerase chain reaction – ligase detection reaction (PCR-LDR)[J] Kai Li;Bei Chen;Yuxun Zhou;Rui Huang;Yinming Liang;Qinxi Wang;Zhenxian Xiao;Junhua Xiao Journal of Microbiological Methods 2008,
[8]
The Impact of a Consortium of Fermented Milk Strains on the Gut Microbiome of Gnotobiotic Mice and Monozygotic Twins Nathan P. McNulty;Tanya Yatsunenko;Ansel Hsiao;Jeremiah J. Faith;Brian D. Muegge;Andrew L. Goodman;Bernard Henrissat;Raish Oozeer;Stéphanie Cools-Portier;Guillaume Gobert;Christian Chervaux;Dan Knights;Catherine A. Lozupone;Rob Knight;Alexis E. Duncan;James R. Bain;Michael J. Muehlbauer;Christopher B. Newgard;Andrew C. Heath;Jeffrey I. Gord; Science Translational Medicine 2011,