胎盘生长因子与妊娠研究进展

被引:3
作者
秦惠芬
乔福元
机构
[1] 华中科技大学同济医学院附属同济医院妇产科
关键词
胎盘生长因子; 妊娠; 滋养细胞; 内皮细胞; 妊娠并发症;
D O I
10.13404/j.cnki.cjbhh.2006.01.004
中图分类号
R714.1 [生理妊娠(正常妊娠)];
学科分类号
100211 ;
摘要
胎盘生长因子(PLGF),通过自分泌和旁分泌机制促进滋养细胞增殖与分化,诱导内皮细胞增殖、迁移、激活,抗内皮细胞凋亡,增加血管通透性。缺氧下调PLGF在滋养细胞的表达。PLGF在正常妊娠胎盘的形成和发育中起重要作用,同时其分泌异常与某些妊娠并发症的发生发展密切相关。
引用
收藏
页码:8 / 9+13 +13
页数:3
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