多囊卵巢综合征对妊娠结局的影响研究进展

被引：76

作者：

李扬璐 ^{[1
]}

阮祥燕 ^{[1
,2
]}

Alfred OMueck ^{[1
,2
]}

机构：

[1] 首都医科大学附属北京妇产医院内分泌科

[2] 德国图宾根大学妇产医院绝经内分泌中心

来源：

首都医科大学学报 | 2016年 / 37卷 / 04期

基金：

北京市自然科学基金;

关键词：

多囊卵巢综合征; 高雄激素血症; 胰岛素抵抗; 卵泡发育; 妊娠结局;

D O I：

暂无

中图分类号：

R711.75 [卵巢疾病];

学科分类号：

100211 [妇产科学];

摘要：

多囊卵巢综合征(polycystic ovary syndrome,PCOS)是育龄期女性最常见的内分泌及代谢紊乱性疾病之一。大多数研究认为,胰岛素抵抗、高雄激素血症和肥胖在PCOS发病过程中起重要作用。临床上观察到PCOS患者常出现妊娠期糖尿病、妊娠高血压疾病等妊娠期合并症。为此,本文对PCOS不良妊娠结局相关因素如PCOS患者卵泡和胚胎发育、子宫内膜容受性的改变以及PCOS与妊娠期合并症的关系做一综述,探讨PCOS患者孕前抗雄激素治疗对其妊娠结局的影响。

引用

页码：449 / 453

页数：5

共 20 条

[1]

The effects of polycystic ovary syndrome on gestational diabetes mellitus [J].

Aktun, Hale Lebriz ;

Yorgunlar, Betul ;

Acet, Mustafa ;

Aygun, Banu Kumbak ;

Karaca, Nilay .

GYNECOLOGICAL ENDOCRINOLOGY, 2016, 32 (02) :139-142

[2]

Endocrine and Reproductive Effects of Polycystic Ovarian Syndrome [J].

Ecklund, Laura C. ;

Usadi, Rebecca S. .

OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA, 2015, 42 (01) :55-+

[3]

Associations Between Insulin Resistance, Free Fatty Acids, and Oocyte Quality in Polycystic Ovary Syndrome During In Vitro Fertilization [J].

Niu, Zhihong ;

Lin, Nan ;

Gu, Ruihuan ;

Sun, Yijuan ;

Feng, Yun .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2014, 99 (11) :E2269-E2276

[4]

Successive and cyclic oral contraceptive pill pretreatment improves IVF/ICSI outcomes of PCOS patients and ameliorates hyperandrogenism and antral follicle excess.[J].Jie-Xue Pan;Ye Liu;Zhang-Hong Ke;Cheng-Liang Zhou;Qing Meng;Guo-Lian Ding;Gu-Feng Xu;Jian-Zhong Sheng;He-Feng Huang.Gynecological Endocrinology.2014, 4

[5]

Increased risk of preterm delivery and pre-eclampsia in women with polycystic ovary syndrome and hyperandrogenaemia [J].

Naver, K. V. ;

Grinsted, J. ;

Larsen, S. O. ;

Hedley, P. L. ;

Jorgensen, F. S. ;

Christiansen, M. ;

Nilas, L. .

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2014, 121 (05) :575-581

[6]

Risks for Gestational Diabetes Mellitus and Pregnancy-Induced Hypertension Are Increased in Polycystic Ovary Syndrome.[J].Yunhui Wang;Xiaomiao Zhao;Huidan Zhao;Hong Ding;Jianping Tan;Jingte Chen;Rui Zhang;Ricardo Azziz;Dongzi Yang;Beverly Muhlhausler.BioMed Research International.2013,

[7]

Disordered follicle development [J].