BDNF及其受体在抗抑郁症中的作用及其机制研究

被引：18

作者：

徐嘉珂

白洁

机构：

[1] 昆明理工大学医学院

来源：

生命科学 | 2014年 / 26卷 / 04期

关键词：

脑源性神经营养因子; 抑郁症; TrkB受体; NMDA受体; 氧化应激;

D O I：

10.13376/j.cbls/2014052

中图分类号：

R749.4 [情感性精神病];

学科分类号：

100204 [神经病学];

摘要：

脑源性神经营养因子(brain-derived neurothrophic factor,BDNF)广泛存在于中枢和外周神经系统,具有神经再生和修复功能。近年来,研究发现BDNF在改善抑郁发生过程中神经可塑性以及抗抑郁药物治疗中发挥重要的作用。综述了BDNF及其受体在抗抑郁症中的作用及其机制研究。

引用

页码：357 / 361

页数：5

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