应激和肠道菌群在肠易激综合征内脏疼痛中的机制研究

被引：18

作者：

詹胜刚

王立生

机构：

[1] 暨南大学第二临床医学院消化内科

来源：

中国微生态学杂志 | 2017年 / 29卷 / 01期

关键词：

IBS; 应激; 内脏痛; 肠道菌群; 微生物-肠-脑轴;

D O I：

暂无

中图分类号：

R574 [肠疾病];

学科分类号：

100201 [内科学];

摘要：

内脏痛是一种躯体内脏器官引起的疼痛,是功能性胃肠病(FGIDs)如肠易激综合征(irritable bowel syndrome,IBS)最常见的临床症状。慢性应激被认为是IBS的发病病因之一,应激可调节脑一肠轴的结构和功能,同时激活肠道免疫,破坏肠道黏膜屏障以及引起内脏感觉过敏。近年来,肠道微生物与脑一肠轴的双向交流及相互作用逐渐被认识,本研究就应激与肠道菌群在IBS内脏疼痛的机制研究作一综述。

引用

页码：122 / 125

页数：4

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