NLRP3炎性小体与2型糖尿病及冠心病并发症的关系

被引：12

作者：

胡龙江 ^{[1
]}

周音频 ^{[1
]}

吕湛 ^{[2
]}

宁琳 ^{[1
]}

向立权 ^{[1
]}

机构：

[1] 重庆市涪陵中心医院心血管内科

[2] 川北医学院附属医院心血管内科

来源：

中华临床医师杂志(电子版) | 2015年 / 9卷 / 23期

关键词：

糖尿病,2型; 冠心病; 炎性小体; 炎性反应;

D O I：

暂无

中图分类号：

R587.2 [糖尿病性昏迷及其他并发症]; R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

100201 [内科学];

摘要：

NLRP3炎性小体是炎性免疫反应的重要组成部分,它能够识别内源性危险信号,激活caspase-1,继而活化白细胞介素IL-1β和IL-18等细胞因子,参与诸多慢性疾病体内非感染性炎性反应。本文拟对NLRP3炎性小体与慢性炎性疾病2型糖尿病及冠心病并发症的关系作一综述。

引用

页码：4428 / 4431

页数：4

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