腰椎间盘退变相关基因的研究

被引：11

作者：

孙正明

刘淼

张银刚

机构：

[1] 西安交通大学医学院第一附属医院骨科

来源：

中华骨科杂志 | 2008年 / 06期

关键词：

D O I：

暂无

中图分类号：

R681.5 [脊柱及背疾病];

学科分类号：

100220 [骨科学];

摘要：

<正>以往认为腰椎间盘病变是由生理性退变、椎间盘损伤、脊柱过度负荷、吸烟等多种因素引起[1-3]。但是,近年来的研究发现遗传因素在椎间盘病变发生、发展中可能扮演着最重要的角色[4-7]。不少研究者认为腰椎间盘突出症是由多个微效基因和环境因素共同作用、积累到一定程度导致的一种复杂性疾病,研究环境因素在腰椎间盘突出症中作用的同时,还须考虑其遗传易感性,

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