房室结消融及起搏器治疗改善心房颤动患者心功能和生活质量的研究

被引:10
作者
范洁
丁立群
周乐今
邓旭
谢红
苗云波
张云梅
机构
[1] 云南省第一人民医院心内科
[2] 云南省第一人民医院心内科 云南昆明
[3] 云南昆明
关键词
心血管病学; 心房颤动; 房室结消融; 起搏器; 心功能; 生活质量;
D O I
10.13333/j.cnki.cjcpe.2004.04.006
中图分类号
R541.7 [心律失常];
学科分类号
1002 ; 100201 ;
摘要
探讨房室结消融 +VVIR起搏器 (ABL +PM)治疗对永久性心房颤动 (简称房颤 )患者生活质量、心功能的改善及评估该治疗的安全性。选择 30例永久性房颤患者 ,14行例ABL +PM治疗 ,16例行药物治疗。治疗前及治疗后 12个月所有患者均做GWB和CSS生活质量评分 ,心脏超声测左室内径及射血分数值 ,活动平板测运动耐力 ,用Holter记录最快、最慢心率。并观察治疗后临床事件的发生。结果 :永久性房颤患者ABL +PM或药物治疗前、后组内比较 ,患者心室率、心功能、运动耐力及生活质量均得到改善 (P <0 .0 5 ) ;但ABL +PM组左室内径缩小 (P <0 .0 5 ) ,药物治疗组无改变 (P >0 .0 5 )。ABL +PM或药物治疗后 12个月组间比较 ,ABL +PM组心室率控制、左室内径、心功能、运动耐力及生活质量改善优于药物组 (P <0 .0 5 )。再次住院人次ABL +PM组较药物组减少 (P <0 .0 5 ) ,死亡、恶性室性心律失常和血栓栓塞事件两组无差异 (P >0 .0 5 )。结论 :ABL +PM或药物治疗均能改善永久性房颤患者心功能、运动耐力及生活质量 ,但ABL +PM优于药物治疗。ABL +PM是一种简单易行安全的治疗方法。
引用
收藏
页码:17 / 19
页数:3
相关论文
共 8 条
[1]  
Effect of irregular ventricular rhythm on cardiac output. Daoud E,Weiss R,Bahu M,et al. The American Journal of Cardiology . 1996
[2]  
Transient proarrhythmic state following atrioventricular junction radiofrequency ablation: Pathophysiological mechanisms and recommendations for management. Nowinski K,Gadler F,Jensen-Urastad M,et al. The American Journal of Medicine . 2002
[3]  
Sudden death after radiofrequency ablation of the atrioventricular node in patients with atrial fibrillation. Ozcan C,Jahangir A,Friedman PA,et al. Journal of the American College of Cardiology . 2002
[4]  
Assessment of atrioventricular junction ablation and VVIR pacemaker versus pharmacological treatment in patients with heart failure and atrial fibrillation. Brignol M,Menozzi C,Gianfranchi L,et al. Circulation . 1998
[5]  
The Australian intervention randomized control of rate in atrial fibrillation trial. Weerassooriya R,Davis M,Powell A,et al. Journal of the American College of Cardiology . 2003
[6]  
Quality of life in patients treated with atrioventricular synchronous pacing compared to rate modulated ventricular pacing: A long-term, double-blind, crossover study. Linde-Edelstam C,Nordlander R,Unden AL,et al. Pacing and Clinical Electrophysiology . 1992
[7]  
AV node ablation and pacemaker implantation after withdrawal of effective rate-control medication for chronic atrial fibrillation: Effect on quality of life and exercise performance. Natal A,Zimerman L,Tomassssssoni G,et al. Pacing and Clinical Electrophysiology . 1999
[8]  
Long-term survival after ablation of atrioventricular node and plantation of a permanent pacemaker in patients with atrial fibrillation. Ozcan C,Jahangir A,Friedman PA,et al. The New England Journal of Medicine . 2001