2型糖尿病合并高血压患者胰岛素抵抗与C反应蛋白、肿瘤坏死因子的关系研究

被引:8
作者
张天弼
冯慧斌
林斌
杜雪霞
陈小龙
吴明清
机构
[1] 汕头大学医学院附属粤北人民医院综合内科
关键词
2型糖尿病; C反应蛋白; 肿瘤坏死因子-α; 胰岛素抵抗指数;
D O I
10.14163/j.cnki.11-5547/r.2011.27.118
中图分类号
R587.1 [糖尿病];
学科分类号
1002 ; 100201 ;
摘要
目的探讨2型糖尿病合并高血压患者胰岛素抵抗与C反应蛋白(CRP)、肿瘤坏死因子(TNF-α)的关系。方法设正常组50例,糖尿病合并高血压患者组60例。检测患者血清空腹胰岛素、C肽、C反应蛋白(CRP)、肿瘤坏死因子(TNF-α)水平及胰岛素抵抗指数(HOMA-IR)程度。结果糖尿病合并高血压患者组与正常组C反应蛋白(CRP)、肿瘤坏死因子(TNF-α),胰岛素抵抗指数(IR)相比,差异有统计学意义(P<0.001)。结论 2型糖尿病合并高血压患者胰岛素抵抗与C反应蛋白(CRP)、肿瘤坏死因子(TNF-α)显著呈正相关。
引用
收藏
页码:6 / 7
页数:2
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