二肽基肽酶-4心血管系统作用的研究进展

被引：6

作者：

陆迪菲

马晓伟

郭晓蕙

机构：

[1] 北京大学第一医院内分泌科

来源：

中国糖尿病杂志 | 2016年 / 24卷 / 11期

关键词：

二肽基肽酶-4; 糖尿病,2型; 心血管系统;

D O I：

暂无

中图分类号：

R96 [药理学];

学科分类号：

100706 [药理学];

摘要：

随着肠促胰素相关研究的不断深入,人们发现,二肽基肽酶-4(DPP-4)抑制剂除了降糖作用外,一些大型临床研究证实了其心血管系统的安全性,并可能通过降低心血管危险因素、改善血管内皮功能等机制起到心血管保护作用。然而,近期也有研究提出DPP-4抑制剂具有促进心力衰竭的可能。本文就DPP-4在心血管方面作用的研究进展进行文献综述。

引用

页码：1049 / 1051

页数：3

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