药物性肝病

被引:13
作者
陈成伟
机构
[1] 南京军区肝病临床研究中心
关键词
D O I
10.14000/j.cnki.issn.1008-1704.2012.05.029
中图分类号
R595.3 [药源性疾病];
学科分类号
100201 [内科学];
摘要
<正>目前药物性肝损伤(DILI)越来越引起人们重视。DILI是发达国家急性肝功能衰竭(ALF)的首要病因,也是美国食品药品监督管理局(FDA)对药物采取警示的最常见原因。发展为ALF者,自然恢复率仅约25%。DILI的发生率约为1/10000~1/1000000暴
引用
收藏
页码:297 / 300
页数:4
相关论文
共 5 条
[1]
药物性肝炎组织病理学评分探讨 [J].
胡锡琪 .
肝脏, 2010, 15 (05) :317-319
[2]
Mitochondrial Superoxide Dismutase and Glutathione Peroxidase in Idiosyncratic Drug-Induced Liver Injury [J].
Lucena, M. Isabel ;
Garcia-Martin, Elena ;
Andrade, Raul J. ;
Martinez, Carmen ;
Stephens, Camilla ;
Ruiz, Jhon D. ;
Ulzurrun, Eugenia ;
Carmen Fernandez, M. ;
Romero-Gomez, Manuel ;
Castiella, Augustin ;
Planas, Ramon ;
Antonio Duran, Jose ;
Melcon De Dios, Ana ;
Guarner, Carlos ;
Soriano, German ;
Borraz, Yolanda ;
Agundez, Jose A. G. .
HEPATOLOGY, 2010, 52 (01) :303-312
[3]
Causality Assessment in Drug-Induced Liver Injury Using a Structured Expert Opinion Process: Comparison to the Roussel-Uclaf Causality Assessment Method [J].
Rockey, Don C. ;
Seeff, Leonard B. ;
Rochon, James ;
Freston, James ;
Chalasani, Naga ;
Bonacini, Maurizio ;
Fontana, Robert J. ;
Hayashi, Paul H. .
HEPATOLOGY, 2010, 51 (06) :2117-2126
[4]
Causality Assessment in Drug-Induced Liver Injury [J].
Hayashi, Paul H. .
SEMINARS IN LIVER DISEASE, 2009, 29 (04) :348-356
[5]
Incidence of drug-induced liver injury in medical inpatients [J].
Meier, Y ;
Cavallaro, M ;
Roos, M ;
Pauli-Magnus, C ;
Folkers, G ;
Meier, PJ ;
Fattinger, K .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2005, 61 (02) :135-143