环氧合酶的研究进展

被引:12
作者
朱辉
杨增明
机构
[1] 东北农业大学生命科学学院
[2] 东北农业大学生命科学学院 哈尔滨
[3] 哈尔滨医科大学生理学教研室
[4] 哈尔滨
关键词
环氧合酶; 前列腺素; 环氧合酶抑制剂;
D O I
暂无
中图分类号
R341 [];
学科分类号
1001 ;
摘要
环氧合酶 (COX)是由花生四烯酸合成前列腺素的关键酶。COX 1和COX 2结构相似 ,但在反应底物、抑制剂 ,以及细胞内定位都有明显不同。COX 1和COX 2催化产生的各种前列腺素可调节机体的生理和病理活动。本文主要就COX 1和COX 2两种同工酶在生化结构、基因表达的调节 ,以及生理和病理功能等方面的进展作一简要介绍
引用
收藏
页码:81 / 83
页数:3
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