矽肺纤维化细胞分子机制研究的进展

[1] Tumor necrosis factor receptor deficiency alters matrix metalloproteinase 13/tissue inhibitor of metalloproteinase 1 expression in murine silicosis. Ortiz LA,Lasky J,Gozal E,et al. American Journal of Respiratory and Critical Care Medicine . 2001

[2] Time course of pulmonary response of rats to inhalation of crystalline silica: NF-κB activation, inflammation, cytokine production, and damage. Porter DW,Ye J,Ma J,et al. Inhalation Toxicology . 2002

[3] Silica-induced apoptosis inmurine macrophage:involvement of tumor necrosis factor-αandnuclear factor-κBactivation. Gozal E,Ortiz LA,Zou X,et al. American Journal of Respiratory Cell and Molecular Biology . 2002

[4] Silica-induced activation of cJun-NH2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated via oxidative stress. Shukla A,Timblin CR,Hubbard AK,et al. Cancer Research . 2001

[5] Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK. Ding M,Shi X,Dong Z,et al. Journal of Biological Chemistry . 1999

[6] Apoptosis underlies immunopathogenic mechanisms in acute silicosis. Borges VM,Lopes MF,Falcao H,et al. Am J Respir Cell Mol Biol . 2002

[7] Nitric oxide up-regulates DNA-binding activity of nuclear factor-κB in macrophages stimulated with silica and inflammatory stimulants. Kang JL,Lee K,Castranova V. Molecular and Cellular Biochemistry . 2000

[8] Enhanced nitric oxide and reactive oxygen species production and damage after inhalation of silica. Porter DW,Millecchia L,Robinson VA,et al. American Journal of Physiology Lung Cellular and Molecular Physiology . 2002

[9] Bronchial epithelial cell matrix production in response to silica and basic fibroblast growth factor. Bodo M,Baroni T,Bellocchio S,et al. Molecular Medicine . 2001

[10] Nuclear factor-κB activation in silica-induced interleukin 8 production by human bronchial epithelial cells. Desaki M,Takizawa H,Kasama T,et al. Cytokine . 2000

[1] Tumor necrosis factor receptor deficiency alters matrix metalloproteinase 13/tissue inhibitor of metalloproteinase 1 expression in murine silicosis. Ortiz LA,Lasky J,Gozal E,et al. American Journal of Respiratory and Critical Care Medicine . 2001

[2] Time course of pulmonary response of rats to inhalation of crystalline silica: NF-κB activation, inflammation, cytokine production, and damage. Porter DW,Ye J,Ma J,et al. Inhalation Toxicology . 2002

[3] Silica-induced apoptosis inmurine macrophage:involvement of tumor necrosis factor-αandnuclear factor-κBactivation. Gozal E,Ortiz LA,Zou X,et al. American Journal of Respiratory Cell and Molecular Biology . 2002

[4] Silica-induced activation of cJun-NH2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated via oxidative stress. Shukla A,Timblin CR,Hubbard AK,et al. Cancer Research . 2001

[5] Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK. Ding M,Shi X,Dong Z,et al. Journal of Biological Chemistry . 1999

[6] Apoptosis underlies immunopathogenic mechanisms in acute silicosis. Borges VM,Lopes MF,Falcao H,et al. Am J Respir Cell Mol Biol . 2002

[7] Nitric oxide up-regulates DNA-binding activity of nuclear factor-κB in macrophages stimulated with silica and inflammatory stimulants. Kang JL,Lee K,Castranova V. Molecular and Cellular Biochemistry . 2000

[8] Enhanced nitric oxide and reactive oxygen species production and damage after inhalation of silica. Porter DW,Millecchia L,Robinson VA,et al. American Journal of Physiology Lung Cellular and Molecular Physiology . 2002

[9] Bronchial epithelial cell matrix production in response to silica and basic fibroblast growth factor. Bodo M,Baroni T,Bellocchio S,et al. Molecular Medicine . 2001

[10] Nuclear factor-κB activation in silica-induced interleukin 8 production by human bronchial epithelial cells. Desaki M,Takizawa H,Kasama T,et al. Cytokine . 2000