转录调节因子核因子κB参与调控的急性肺损伤相关的细胞因子基因

被引:15
作者
曹建
廖品琥
机构
[1] 广西医科大学肿瘤医院麻醉科
关键词
核因子; 急性肺损伤; 基因;
D O I
暂无
中图分类号
R563.8 [呼吸衰竭];
学科分类号
100201 [内科学];
摘要
转录调节因子核因子(NF-κB)的活化与灭活,直接参与调节多种与急性肺损伤(ALI)相关的炎性细胞因子及黏附因子的基因转录。NF-κB的活化与炎性细胞因子的表达及肺损伤之间有正相关性。本文综述了NF-κB的结构和生物学特性、活化的因素及调节、与细胞因子的基因结合位点及炎性细胞因子的基因转录和表达的关系及其在ALI中的作用。
引用
收藏
页码:1526 / 1528
页数:3
相关论文
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