脂蛋白相关磷脂酶A2与缺血性脑卒中的研究进展

被引：3

作者：

徐邦娴

邓远飞

机构：

[1] 北京大学深圳医院特诊老年病科

来源：

中国现代医生 | 2015年 / 53卷 / 14期

关键词：

脂蛋白相关磷脂酶A2; 缺血性脑卒中; 动脉粥样硬化; 炎症标志物;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

1002 ;

摘要：

动脉粥样硬化是缺血性脑卒中的主要病因,脂蛋白相关磷脂酶A2(Lp-PLA2)作为新型炎症标志物参与动脉粥样硬化形成,并与斑块易损性相关。目前研究认为Lp-PLA2在评估动脉粥样硬化性缺血性脑卒中的危险分层及复发风险中有重要作用,将成为动脉粥样硬化性缺血性脑卒中的独立预测因子。本文从Lp-PLA2的生物学特征、在AS中的双重作用及其与颈动脉粥样硬化、缺血性脑卒中的相关性等方面进行综述。

引用

页码：152 / 155+160 +160

页数：5

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