三磷酸腺苷脂质体的研究

被引：6

作者：

徐国兴

谢星辉

机构：

[1] 国家医药管理局上海医药工业研究院

[2] 国家医药管理局上海医药工业研究院上海无锡华瑞制药有限公司

[3] 上海

来源：

药学学报 | 1989年 / 02期

关键词：

靶向给药系统; 脂质体; 乳化法; 三磷酸腺苷;

D O I：

10.16438/j.0513-4870.1989.02.012

中图分类号：

学科分类号：

摘要：

In this paper, a method——improved emulsification vesicles (IEV) was proposed for the preparation of adenosine triphosphate (ATP) liposome The-ATP entrapment ratio reached 38.9% (w/w), which was much greater than that reported in the literature. Thus, IEV is an excellent method which has never been presented. Together with ultrafiltration for removing unentrapped drugs and radiation sterilization, these methods are most meaningful for the production of liposomes in large scale.

引用

页码：133 / 138

页数：6