脂蛋白相关磷脂酶A2与动脉粥样硬化相关研究进展

被引:6
作者
卓明峰 [1 ]
徐尚华 [2 ]
机构
[1] 福建中医学院
[2] 福建省南平市第一医院心内一区
关键词
脂蛋白相关性磷脂酶A2; 动脉粥样硬化; 冠心病;
D O I
10.14163/j.cnki.11-5547/r.2009.05.073
中图分类号
R543.5 [动脉疾病];
学科分类号
1002 ; 100201 ;
摘要
血浆脂蛋白相关磷脂酶A2(LP-PLA2)由成熟的巨噬细胞和淋巴细胞合成和分泌,又称血小板活化因子乙酰水解酶(PAF-AH),在血浆中主要与低密度脂蛋白结合。近年来,越来越多研究表明在动脉粥样硬化的发病机制及预防性治疗上,LP-PLA2是动脉粥样硬化中的一个新的炎性反应标志物,可能成为冠心病治疗的新靶点。
引用
收藏
页码:226 / 230
页数:5
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