高雄激素血症检测项目与雄激素测定方法

被引:4
作者
黄美凤
赵晓苗
杨冬梓
机构
[1] 中山大学孙逸仙纪念医院生殖中心
关键词
多囊卵巢综合征; 雄激素增多症; 放射免疫测定; 色谱法,高压液相;
D O I
暂无
中图分类号
R711.75 [卵巢疾病];
学科分类号
100211 [妇产科学];
摘要
高雄激素血症是多囊卵巢综合征(polycystic ovarian syndrome,PCOS)的基本特征之一。由于PCOS在育龄女性中发病率高,故早发现、早治疗对该病尤其重要。目前全世界可进行雄激素检测的医院中,仍在用酶联免疫吸附测定(ELISA)法检测游离雄激素,化学发光法检测总雄激素。国际上已有许多关于雄激素检测的方法,结果显示,这些方法在检测女性低血清雄激素水平的敏感度较差;同时雄激素的测定项目至今仍未取得一致共识。这提示目前可能有大部分伴有高雄激素血症的患者未得到诊断。放射免疫法及质谱法定量检测雄激素是较为准确的检测方法,但因各种因素未能应用于临床,对PCOS的诊断和治疗造成很大困难。
引用
收藏
页码:115 / 118
页数:4
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