肠道菌群失衡在结直肠癌发病过程中的作用

被引:20
作者
徐艳丽 [1 ]
尹霞 [2 ]
常英 [1 ]
机构
[1] 上海交通大学附属第六人民医院消化内镜室
[2] 苏州大学医学部
关键词
肠道微生物; 肠道菌群; 结直肠癌; 益生菌;
D O I
暂无
中图分类号
R735.34 [];
学科分类号
摘要
结直肠癌是结肠癌和直肠癌的总称,目前其病因和发病机制尚未明确。现认为结直肠癌的发生可能与肠道微环境、宿主遗传易感性和高动物蛋白饮食等因素有关。近年来,随着微生态学的发展,肠道菌群与结直肠癌发病的关系日益受到关注。此文就结直肠癌发生过程中肠道菌群的变化、对结直肠癌的影响以及微生态制剂对结直肠癌的治疗作用等相关研究作一综述。
引用
收藏
页码:124 / 127
页数:4
相关论文
共 14 条
[1]
Global Cancer Statistics; 2002.[J].D. MaxParkin;FreddieBray;J.Ferlay;PaolaPisani.CA: A Cancer Journal for Clinicians.2009, 2
[2]
Dietary Modification of the Intestinal Microbiota.[J].VolkerMai.Nutrition Reviews.2008, 6
[3]
Influence of Dietary Fiber on Inflammatory Bowel Disease and Colon Cancer: Importance of Fermentation Pattern.[J].Devin J.Rose;Mark T.DeMeo;AliKeshavarzian;Bruce R.Hamaker.Nutrition Reviews.2008, 2
[4]
Multiplex quantification of 16S rDNA of predominant bacteria group within human fecal samples by polymerase chain reaction – ligase detection reaction (PCR-LDR).[J].Kai Li;Bei Chen;Yuxun Zhou;Rui Huang;Yinming Liang;Qinxi Wang;Zhenxian Xiao;Junhua Xiao.Journal of Microbiological Methods.2008, 3
[5]
Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis [J].
Scanlan, Pauline D. ;
Shanahan, Fergus ;
Clune, Yvonne ;
Collins, John K. ;
O'Sullivan, Gerald C. ;
O'Riordan, Micheal ;
Holmes, Elaine ;
Wang, Yulan ;
Marchesi, Julian R. .
ENVIRONMENTAL MICROBIOLOGY, 2008, 10 (03) :789-798
[6]
Antigenotoxicity of probiotics and prebiotics on faecal water-induced DNA damage in human colon adenocarcinoma cells.[J].Anthony J Burns;Ian R Rowland.Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis.2004, 1
[7]
Effect of coconut cake on the bacterial enzyme activity in 1;2-dimethyl hydrazine induced colon cancer.[J].Namasivayam Nalini;Vaiyapuri Manju;Venugopal P. Menon.Clinica Chimica Acta.2004, 1
[8]
The microbiology of butyrate formation in the human colon [J].
Pryde, SE ;
Duncan, SH ;
Hold, GL ;
Stewart, CS ;
Flint, HJ .
FEMS MICROBIOLOGY LETTERS, 2002, 217 (02) :133-139
[9]
The intestinal microflora and its colon cancer connection.[J].S. L. Gorbach.Infection.1982, 6
[10]
结直肠癌围手术期替代应用肠道微生态制剂对肠道菌群及机体免疫功能的影响.[J].朱达坚;陈小伍;伍锦浩;剧永乐;封静;陆光生;欧阳满照;任宝军;李泳;.南方医科大学学报.2012, 08