老年2型糖尿病患者并发冠心病的危险因素分析

被引:21
作者
郭立新
马靖
程洋
张丽娜
潘琦
王晓霞
机构
[1] 卫生部北京医院内分泌科
关键词
糖尿病,2型; 冠心病; 主成分分析; 白蛋白尿;
D O I
暂无
中图分类号
R587.1 [糖尿病]; R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
100201 [内科学];
摘要
目的应用主成分分析法(principal component analysis,PCA)分析老年2型糖尿病患者并发冠心病的主要危险因素。方法回顾性分析我院住院行冠状动脉(冠脉)造影检查的60岁以上老年2型糖尿病患者503例临床资料,测定糖尿病患者尿白蛋白排泄率(urinary albuminexcretion rate,UAER)等指标,采用Gensini系统对冠脉血管病变程度进行评分。结果第1~7主成分的特征值均大于1,累计贡献率为64.6%;第1~4主成分分别为UAER、血脂、血压、尿酸,贡献率分别为14.1%、11.8%、10.2%、8.7%;第5~7主成分均属血糖,累计贡献率为19.8%。结论 UAER是老年2型糖尿病患者并发冠心病最主要的危险因素,伴微量白蛋白尿的老年2型糖尿病患者冠心病患病风险增加,且严重程度增加;UAER与老年2型糖尿病患者冠心病的发生及冠脉病变严重程度呈正相关,为其独立影响因素。
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