缺血性卒中再发危险因素分析

被引:14
作者
窦汝香
李卓星
林凯思
郭珍万
杨瑞琦
机构
[1] 深圳市龙岗区布吉人民医院神经内科
关键词
脑梗死; C反应蛋白; 纤维蛋白原; 危险因素;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
摘要
目的探讨缺血性卒中再发的危险因素。方法收集我院急性缺血性卒中病例195例,收集患者资料:年龄、既往吸烟、高血压病、糖尿病史,入院后检测血脂、同型半胱氨酸、纤维蛋白原(fibrinogen,Fg)、超敏C反应蛋白(high sensitiveC-reactive protein,hsC—RP)、颈动脉超声等。对病例进行随访2年,患者分为缺血性卒中再发组和缺血性卒中无再发组2组,分析以上因素在两组间的差异。结果 195例患者入选,3例因其他系统疾病死亡失访,192例参加随访的缺血性卒中病例中52例再发,再发率27.1%。单因素分析显示,缺血性卒中再发组的年龄、hsC—RP、Fg水平显著高于缺血性卒中无再发组;糖尿病、高血压病、颈动脉斑块发生率也明显高于缺血性卒中无再发组。多因素分析显示,hsC-RP>3mg/L[比值比(odds ratio,OR)=2.72;95%置信区间(confidenceinterval,CI)1.35~5.46;P=0.005)、Fg>4g/L(OR=2.31;95 c%CI 1.16~4.58;P=0.017)与缺血性卒中再发独立相关。结论缺血性卒中急性期hsC-RP、Fg增高是缺血性卒中再发的独立危险因素。
引用
收藏
页码:454 / 458
页数:5
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