乙型肝炎的肝脏免疫学和免疫治疗

被引：4

作者：

王福生

机构：

[1] 解放军第三二医院生物治疗研究中心

来源：

中国继续医学教育 | 2010年 / 2卷 / 03期

关键词：

D O I：

暂无

中图分类号：

R512.62 [];

学科分类号：

摘要：

<正>乙型肝炎病毒(HBV)是一种DNA病毒(属于嗜肝DNA病毒科),可引起急性肝炎、慢性肝炎,肝硬化和肝癌[1]。研究提示病毒本身、人体免疫系统和肝脏病理是影响疾病进展、临床预后三大因素,其中机体抗HBV免疫学应答的作用贯穿临床发

引用

页码：46 / 49+86 +86

页数：5

共 6 条

[1]

Host immunity influences disease progression and antiviral efficacy in humans infected with hepatitis B virus.[J].Wang;Zhang.Expert Review of Gastroenterology & Hepatology.2009, 5

[2]

Transfusion of autologous cytokine-induced killer cells inhibits viral replication in patients with chronic hepatitis B virus infection [J].

Shi, Ming ;

Fu, Junliang ;

Shi, Feng ;

Zhang, Bin ;

Tang, Zirong ;

Jin, Lei ;

Fan, Zhenping ;

Zhang, Zheng ;

Chen, Liming ;

Wang, Huifeng ;

Lau, George K. K. ;

Wang, Fu-Sheng .

CLINICAL IMMUNOLOGY, 2009, 132 (01) :43-54

[3]

Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B [J].

Zhang, Zheng ;

Zhang, Ji-Yuan ;

Wherry, E. John ;

Jin, Bo ;

Xu, Bin ;

Zou, Zheng-Sheng ;

Zhang, Shu-Ye ;

Li, Bao-Sen ;

Wang, Hui-Feng ;

Wu, Hao ;

Lau, George K. K. ;

Fu, Yang-Xin ;

Wang, Fu-Sheng .

GASTROENTEROLOGY, 2008, 134 (07) :1938-1949

[4]

Severe dendritic cell perturbation is actively involved in the pathogenesis of acute-on-chronic hepatitis B liver failure [J].

Zhang, Zheng ;

Zou, Zheng-Sheng ;

Fu, Jun-Liang ;

Cai, Lun ;

Jin, Lei ;

Liu, Yong-Jun ;

Wang, Fu-Sheng .

JOURNAL OF HEPATOLOGY, 2008, 49 (03) :396-406

[5]

Increased infiltration of intrahepatic DC subsets closely correlate with viral control and liver injury in immune active pediatric patients with chronic hepatitis B [J].

Zhang, Zheng ;

Chen, Dawei ;

Yao, Jinxia ;

Zhang, Hui ;

Jin, Lei ;

Shi, Ming ;

Zhang, Hongfei ;

Wang, Fu-Sheng .

CLINICAL IMMUNOLOGY, 2007, 122 (02) :173-180

[6]

Incubation phase of acute hepatitis B in man: Dynamic of cellular immune mechanisms [J].

Webster, GJM ;

Reignat, S ;

Maini, MK ;

Whalley, SA ;

Ogg, GS ;

King, A ;

Brown, D ;

Amlot, PL ;

Williams, R ;

Vergani, D ;

Dusheiko, GM ;

Bertoletti, A .

HEPATOLOGY, 2000, 32 (05) :1117-1124

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