竹茹多糖体外调节肠道菌群的作用研究

被引：99

作者：

黄菊青

林斌

徐庆贤

官雪芳

钱蕾

郑怡

机构：

[1] 福建省农业科学院农业工程技术研究所福建省农产品(食品)加工重点实验室

来源：

营养学报 | 2019年 / 01期

关键词：

竹茹多糖; 体外发酵; 肠道菌群; 短链脂肪酸;

D O I：

暂无

中图分类号：

R151 [营养学];

学科分类号：

100403 [营养与食品卫生学];

摘要：

目的研究竹茹多糖体外调节人体肠道菌群的作用,为竹茹多糖作为肠道微生态调节剂的研发提供理论依据。方法通过体外模拟发酵体系考察竹茹多糖对人体肠道菌群的调节作用;采用16S rDNA高通量测序技术分析肠道菌群组成,采用GC-MS法检测菌群代谢产物（短链脂肪酸）。结果竹茹多糖能够显著上调拟杆菌属、普雷沃茨菌属、双歧杆菌属、乳杆菌属、副拟杆菌属、考拉杆菌属、氨基酸球菌属、布劳特氏菌、严格厌氧梭菌属13、Erysipelatoclostridium属、链型杆菌属、Flavonifractor属和韦荣球菌属的相对丰度,并显著下调梭杆菌属、嗜胆菌属、脱硫弧菌属、另枝菌属、Butyricimonas属、Butyricicoccus属、Eisenbergiella属、Faecalitalea属、Lachnoclostridium属、LachnospiraceaeUCG-004属、LachnospiraceaeUCG-008属、Lachnospiraceaeuncultured属、罕见小球菌属和土孢杆属的相对丰度;同时,竹茹多糖能够显著促进人体肠道菌群代谢产生乙酸、丙酸和丁酸。结论竹茹多糖能够显著调节人体肠道菌群,并促进其代谢产生有益于机体健康的短链脂肪酸。[营养学报,2019,41（1）:45-52]

引用

页码：45 / 52

页数：8

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