原发性胆汁性肝硬化的药物治疗进展

被引：9

作者：

张华伟 ^{[1
]}

张艳 ^{[2
]}

杨镜 ^{[2
]}

徐凌 ^{[2
]}

卢洁 ^{[2
]}

郭传勇 ^{[2
]}

机构：

[1] 苏州大学附属第一医院消化科

[2] 同济大学附属第十人民医院消化科

来源：

世界临床药物 | 2014年 / 35卷 / 04期

关键词：

原发性胆汁性肝硬化; 药物治疗; 熊去氧胆酸;

D O I：

10.13683/j.wph.2014.04.006

中图分类号：

R575.22 [];

学科分类号：

摘要：

原发性胆汁性肝硬化(PBC)是一种病因未明的慢性进行性胆汁淤积性肝脏疾病。熊去氧胆酸是目前最具循证医学支持的PBC治疗药物,但约40%PBC患者对熊去氧胆酸治疗应答不良。本文综述糖皮质激素、免疫抑制剂、贝特类降脂药、抗逆转录病毒药物以及利妥昔单抗等临床常用药物和某些临床有可能选用的联合治疗方案。

引用

页码：253 / 256

页数：4

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