咳嗽变异性哮喘与白三烯关系的研究进展

被引：12

作者：

方芬

谭毅

机构：

[1] 常德市妇幼保健院儿科

来源：

中国临床新医学 | 2013年 / 6卷 / 01期

关键词：

咳嗽变异性哮喘; 白三烯; 治疗;

D O I：

暂无

中图分类号：

R562.25 [];

学科分类号：

摘要：

咳嗽变异性哮喘(CVA)是以咳嗽为唯一或主要临床表现的特殊类型的哮喘,其发病机制及病理生理与典型哮喘相似,两者均以持续气道炎症、气道高反应性和气道重构为特点,平均约有30%的CVA患儿最终发展为典型哮喘。白三烯(LTs)是体内重要的炎症介质,LTs及其拮抗剂在CVA的发病和治疗中起重要作用。在CVA的治疗对策中,早期干预具有重要临床意义,在众多合理、有效的指导与治疗选项中,LTs拮抗剂不失为一项有效、安全的选择。该文就CVA与LTs关系的研究进展作一综述。

引用

页码：87 / 90

页数：4

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